Publications

Publications

  • Ellard KK, Gosai AK, Felicione JM, et al. Deficits in frontoparietal activation and anterior insula functional connectivity during regulation of cognitive-affective interference in bipolar disorder. Bipolar Disord. 2019;21(3):244-258.
  • Basu I, Robertson MM, Crocker B, et al. Consistent linear and non-linear responses to invasive electrical brain stimulation across individuals and primate species with implanted electrodes. Brain Stimul. 2019;
  • Widge AS, Zorowitz S, Basu I, et al. Deep brain stimulation of the internal capsule enhances human cognitive control and prefrontal cortex function. Nat Commun. 2019;10(1):1536.
  • Yousefi, Ali & Basu, Ishita & Paulk, Angelique & Peled, Noam & Eskandar, Emad & Dougherty, Darin & S Cash, Sydney & S Widge, Alik & T Eden, Uri. (2019). Decoding Hidden Cognitive States from Behavior and Physiology using a Bayesian Approach. Preprint at Researchgate.net.
  • Yousefi, Ali, Angelique C. Paulk, Ishita Basu, Darin D. Dougherty, Emad N Eskandar, Uri T Eden, and Alik S Widge. “COMPASS: An Open-Source, General-Purpose Software Toolkit for Computational Psychiatry,” bioRxiv 377556;
    doi: https://doi.org/10.1101/377556
  • Patel SR, Herrington TM, Sheth SA, et al. Intermittent subthalamic nucleus deep brain stimulation induces risk-aversive behavior in human subjects. Elife. 2018;7
  • Bilge MT, Gosai AK, Widge AS. Deep Brain Stimulation in Psychiatry: Mechanisms, Models, and Next-Generation Therapies. Psychiatr Clin North Am. 2018;41(3):373-383.
  • Basu I, Crocker B, Farnes K, et al. A neural mass model to predict electrical stimulation evoked responses in human and non-human primate brain. J Neural Eng. 2018;15(6):066012.
  • Widge, Alik S., Donald A. Malone, and Darin D. Dougherty. “Closing the Loop on Deep Brain Stimulation for Treatment-Resistant Depression.” Frontiers in Neuroscience 12 (March 21, 2018).
    https://doi.org/10.3389/fnins.2018.00175
  • Warner, Graham C., and Karl G. Helmer. “Characterization of Diffusion Metric Map Similarity in Data From a Clinical Data Repository Using Histogram Distances.” Frontiers in Neuroscience 12 (March 8, 2018).
    https://doi.org/10.3389/fnins.2018.00133
  • Martinez-Rubio, Clarissa, Angelique C Paulk, Eric J McDonald, Alik S Widge, and Emad N Eskandar. “Multi-Modal Encoding of Novelty, Reward, and Learning in the Primate Nucleus Basalis of Meynert.” Journal of Neuroscience, 2018, 2021–17.
    https://doi.org/10.1523/JNEUROSCI.2021-17.2017
  • Ellard, Kristen K, Jared P Zimmerman, Navneet Kaur, Koene RA Van Dijk, Joshua L Roffman, Andrew A Nierenberg, Darin D Dougherty, Thilo Deckersbach, and Joan A Camprodon. “Functional Connectivity between Anterior Insula and Key Nodes of Frontoparietal Executive Control and Salience Networks Distinguish Bipolar Depression from Unipolar Depression and Healthy Control Subjects.” Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 3, no. 5 (2018): 473–84.
    https://doi.org/10.1016/j.bpsc.2018.01.013
  • LaPlante, Roan A., Wei Tang, Noam Peled, Deborah I. Vallejo, Mia Borzello, Darin D. Dougherty, Emad N. Eskandar, Alik S. Widge, Sydney S. Cash, and Steven M. Stufflebeam. “The Interactive Electrode Localization Utility: Software for Automatic Sorting and Labeling of Intracranial Subdural Electrodes.” International Journal of Computer Assisted Radiology and Surgery 12, no. 10 (October 2017): 1829–37.
    https://doi.org/10.1007/s11548-016-1504-2
  • Widge, Alik S., Kristen K. Ellard, Angelique C. Paulk, Ishita Basu, Ali Yousefi, Samuel Zorowitz, Anna Gilmour, Afsana Afzal, Thilo Deckersbach, Sydney S. Cash, Mark A. Kramer, Uri T. Eden, Darin D. Dougherty and Emad N. Eskandar. “Treating Refractory Mental Illness with Closed-Loop Brain Stimulation: Progress towards a Patient-Specific Transdiagnostic Approach.” Experimental Neurology 287, no. Pt 4 (January 2017): 461–72.
    https://doi.org/10.1016/j.expneurol.2016.07.021
  • Yousefi, Ali, Reza Kakooee, Mohammad TH Beheshti, Darin D Dougherty, Emad N Eskandar, Alik S Widge, and Uri T Eden. “Predicting Learning Dynamics in Multiple-Choice Decision-Making Tasks Using a Variational Bayes Technique,” 3194–97. IEEE, 2017.
    https://doi.org/10.1109/EMBC.2017.8037536
  • Yousefi, Ali, Darin D Dougherty, Emad N Eskandar, Alik S Widge, and Uri T Eden. “Estimating Dynamic Signals From Trial Data With Censored Values.” Computational Psychiatry 1 (2017): 58–81.
    https://dx.doi.org/10.1162/cpsy_a_00003
  • Deep Brain Stimulation: Clinical Applications.
    Dougherty The Psychiatric clinics of North America (volume 41 issue 3 pages 385-394 ). September 2018
  • Lo, Meng-Chen, and Alik S Widge. “Closed-Loop Neuromodulation Systems: Next-Generation Treatments for Psychiatric Illness.” International Review of Psychiatry 29, no. 2 (2017): 191–204.
    https://doi.org/10.1080/09540261.2017.1282438
  • Dougherty, Darin D, and Alik S Widge. “Neurotherapeutic Interventions for Psychiatric Illness.” Harvard Review of Psychiatry 25, no. 6 (2017): 253–55.
    https://doi.org/10.1097/HRP.0000000000000174
  • Widge, Alik S., Samuel Zorowitz, Katherine Link, Earl K. Miller, Thilo Deckersbach, Emad N. Eskandar, and Darin D. Dougherty. “Ventral Capsule/Ventral Striatum Deep Brain Stimulation Does Not Consistently Diminish Occipital Cross-Frequency Coupling.” Biological Psychiatry 80, no. 7 (October 2016): e59–60.
    https://doi.org/10.1016/j.biopsych.2015.10.029
  • Katnani, Husam A., Shaun R. Patel, Churl-Su Kwon, Samer Abdel-Aziz, John T. Gale, and Emad N. Eskandar. “Temporally Coordinated Deep Brain Stimulation in the Dorsal and Ventral Striatum Synergistically Enhances Associative Learning.” Scientific Reports 6, no. 1 (May 2016).
    https://doi.org/10.1038/srep18806
  • Widge, Alik S, and Amar Sahay. “Closing the Loop in Deep Brain Stimulation for Psychiatric Disorders: Lessons from Motor Neural Prosthetics.” Neuropsychopharmacology 41, no. 1 (2016): 379.
    https://doi.org/10.1038/npp.2015.241
  • Widge, Alik S, Ernesto Licon, Samuel Zorowitz, Andrew Corse, Amanda R Arulpragasam, Joan A Camprodon, Cristina Cusin, Emad N Eskandar, Thilo Deckersbach, and Darin D Dougherty. “Predictors of Hypomania during Ventral Capsule/Ventral Striatum Deep Brain Stimulation.” The Journal of Neuropsychiatry and Clinical Neurosciences 28, no. 1 (2016): 38–44.
    https://doi.org/10.1176/appi.neuropsych.15040089
  • Widge, Alik S, Thilo Deckersbach, Emad N Eskandar, and Darin D Dougherty. “Deep Brain Stimulation for Treatment-Resistant Psychiatric Illnesses: What Has Gone Wrong and What Should We Do Next?” Biological Psychiatry 79, no. 4 (2016): e9–10.
    https://doi.org/10.1016/j.biopsych.2015.06.005
  • Kim, Louis, Jacob Harer, Akshay Rangamani, James Moran, Philip D Parks, Alik Widge, Emad Eskandar, Darin Dougherty, and Sang Peter Chin. “Predicting Local Field Potentials with Recurrent Neural Networks,” 808–11. IEEE, 2016.
    https://doi.org/10.1109/EMBC.2016.7590824
  • Yousefi, Ali, Angelique C Paulk, Thilo Deckersbach, Darin D Dougherty, Emad N Eskandar, Alik S Widge, and Uri T Eden. “Cognitive State Prediction Using an EM Algorithm Applied to Gamma Distributed Data,” 7819–24. IEEE, 2015.
    https://doi.org/10.1109/EMBC.2015.7320205
  • Widge, Alik S, and Darin D Dougherty. “Deep Brain Stimulation for Treatment-Refractory Mood and Obsessive-Compulsive Disorders.” Current Behavioral Neuroscience Reports 2, no. 4 (2015): 187–97.
    https://doi.org/10.1007/s40473-015-0049-y
  • Wheeler, Jesse J, Keith Baldwin, Alex Kindle, Daniel Guyon, Brian Nugent, Carlos Segura, John Rodriguez, Andrew Czarnecki, Hailey J Dispirito, and John Lachapelle. “An Implantable 64-Channel Neural Interface with Reconfigurable Recording and Stimulation,” 7837–40. IEEE, 2015.
    https://doi.org/10.1109/EMBC.2015.7320208
  • Hamilton, Lei, Marc McConley, Kai Angermueller, David Goldberg, Massimiliano Corba, Louis Kim, James Moran, Philip D Parks, Sang Chin, and Alik S Widge. “Neural Signal Processing and Closed-Loop Control Algorithm Design for an Implanted Neural Recording and Stimulation System,” 7831–36. IEEE, 2015.
    https://doi.org/10.3389/Fnins.2018.00133
  • Faghih, Rose T, Patrick A Stokes, Marie-France Marin, Rachel G Zsido, Sam Zorowitz, Blake L Rosenbaum, Huijin Song, Mohammed R Milad, Darin D Dougherty, and Emad N Eskandar. “Characterization of Fear Conditioning and Fear Extinction by Analysis of Electrodermal Activity,” 7814–18. IEEE, 2015.
    https://doi.org/10.1109/EMBC.2015.7320204
  • Deng, Xinyi, Rose T Faghih, Riccardo Barbieri, Angelique C Paulk, Wael F Asaad, Emery N Brown, Darin D Dougherty, Alik S Widge, Emad N Eskandar, and Uri T Eden. “Estimating a Dynamic State to Relate Neural Spiking Activity to Behavioral Signals during Cognitive Tasks,” 7808–13. IEEE, 2015.
    https://doi.org/10.1109/EMBC.2015.7320203
  • Bjune, Caroline K, Thomas F Marinis, Tirunelveli S Sriram, Jeanne M Brady, James Moran, Philip D Parks, Alik S Widge, Darin D Dougherty, and Emad N Eskandar. “Packaging Architecture for an Implanted System That Monitors Brain Activity and Applies Therapeutic Stimulation,” 2015:000548–54. International Microelectronics Assembly and Packaging Society, 2015.
    https://doi.org/10.4071/isom-2015-THA13
  • Bjune, Caroline K, Thomas F Marinis, Jeanne M Brady, James Moran, Jesse Wheeler, Tirunelveli S Sriram, Philip D Parks, Alik S Widge, Darin D Dougherty, and Emad N Eskandar. “Package Architecture and Component Design for an Implanted Neural Stimulator with Closed Loop Control,” 7825–30. IEEE, 2015.
    https://doi.org/10.1109/EMBC.2015.7320206
  • Ahmari, Susanne E, and Darin D Dougherty. “Dissecting OCD Circuits: From Animal Models to Targeted Treatments.” Depression and Anxiety 32, no. 8 (2015): 550–62.
    https://doi.org/10.1002/da.22367
  • LaPlante, Roan A., Linda Douw, Wei Tang, and Steven M. Stufflebeam. “The Connectome Visualization Utility: Software for Visualization of Human Brain Networks.” Edited by Daniele Marinazzo. PLoS ONE 9, no. 12 (December 1, 2014): e113838.
    https://doi.org/10.1371/journal.pone.0113838


Presentations

  • Basu et. Al. A biophysical model of electrical stimulation evoked responses in cortical and subcortical brain regions of human and non-human primates. Poster presented at Society for Neuroscience; Nov 12-16, 2016; San Diego, CA.
  • Paulk et al. Neural Stimulation Induces Changes in Behavior and Neural Responsiveness in the Emotion Conflict Resolution (ECR) Task. Poster presented at Society for Neuroscience; Nov 12-16, 2016; San Diego, CA.
  • Robertson et al. An exploration of stimulation effects in the non-human primate brain. Poster presented at Society for Neuroscience; November 12-16, 2016; San Diego, CA.
  • Yousefi et al. Characterizing Stimulation-Evoked Synchrony in Brain Networks. Poster presented at Society for Neuroscience; Nov 12-16, 2016; San Diego, CA.
  • Basu et al. A biophysical model predicts electrical stimulation evoked response in cortical and subcortical brain regions. Poster presented at North American Neuromodulation Society; June 2-29, 2016; Baltimore, MD.
  • Gilmour et at. A Multimodal Transdiagnostic Assessment of Emotional Regulation. Poster presented at Society of Biological Psychiatry; May 12-14, 2016; Atlanta, GA.
  • Zorowitz et at. Bayesian State-Space Modeling of Reversal Learning: A Methodological Innovation for fMRI. Poster presented at Society for Biological Psychiatry;May 12-14, 2016; Atlanta, GA.
  • Dougherty D, Neurosurgical Treatments for Refractory Psychiatric Illness:From Lesions to Stimulation, International Science Symposium March 2015